Early days, but interesting Tower Defense in the expand your path genre. Developer is obviously still finishing the game, but this is not a serious drawback as most of the bells and whistles are there. Graphics are good (I prefer the 3D) and most of the menu's are complete. The finishing of the enemy details menu should be most helpful. I wouldn't mind seeing a game speed option (could be on the to-do list) as the levels can draw out a bit. I will watch with interest (plus I think my medical knowledge may have expanded)!!
STEM Defense
- Release Date:
- Jun 7, 2024
- Developer:
- NoOneGames
- Publisher:
- NoOneGames
- Platforms:
- Windows Mac
Game Tags
About This Game

Iimmerses yourself in a strategic battle within the human body, where you manipulate pathways and tower placements on a dynamic hexagonal grid. This educational tower defense game teaches players about the immune system through engaging gameplay, focusing on the defense against microscopic invaders.
Key Features
Path Expansion: Dynamically extend the pathways pathogens travel to strategically shape each level and increase the effectiveness of your defenses.
Tower Placement Strategy: Strategic placement of your towers is essential. Elevate your towers to gain damage bonuses, crucial for optimizing defense effectiveness.
Mutation-Based Upgrades: Enhance your defenses through epigenetic modifications, providing temporary boosts, and genetic mutations for permanent enhancements. This mirrors real-life biological defense mechanisms.
Experience and Genetic Enhancements: Gain experience to unlock advanced defensive capabilities and permanent genetic upgrades, enhancing your ability to combat pathogens.
Varied Enemy Types: Encounter diverse pathogens, each with unique abilities. Develop strategies to handle enemies that can regenerate, accelerate, or spawn additional threats.
Endless Replayability: With a multitude of genetic enhancements and adaptive enemy tactics, each game offers new challenges and decisions, ensuring unique experiences with every playthrough.
Coming Soon: Acquired immunity mechanics!!
Support Independent Development
As a solo developer not well-versed in the art of social media, I rely on the support of players like you. If you've enjoyed "STEM Defense", please help spread the word and make it known to others!
Screenshots
User Reviews
System Requirements
Minimum
- OS: Windows 10
- Processor: Intel i5
- Memory: 4 GB RAM
- Graphics: NVIDIA GeForce 8600 GT / AMD Radeon HD 2600XT (at least 256 MB video memory) Network: Broadband internet connection
- DirectX: Version 10
- Storage: 500 MB available space
- Sound Card: DirectX compatible
Recommended
- OS: Windows 10
- Processor: Intel Core i5-8400 or AMD Ryzen 5 2600
- Memory: 8 GB RAM
- Graphics: NVIDIA GeForce GTX 1060 6GB or AMD Radeon RX 580 8GB
- DirectX: Version 12
- Storage: 1 GB available space
- Sound Card: DirectX compatible, with latest drivers
FAQ
How much does STEM Defense cost?
STEM Defense costs $9.99.
What are the system requirements for STEM Defense?
Minimum: Minimum: OS: Windows 10 Processor: Intel i5 Memory: 4 GB RAM Graphics: NVIDIA GeForce 8600 GT / AMD Radeon HD 2600XT (at least 256 MB video memory) Network: Broadband internet connection DirectX: Version 10 Storage: 500 MB available space Sound Card: DirectX compatible Recommended: Recommended: OS: Windows 10 Processor: Intel Core i5-8400 or AMD Ryzen 5 2600 Memory: 8 GB RAM Graphics: NVIDIA GeForce GTX 1060 6GB or AMD Radeon RX 580 8GB DirectX: Version 12 Storage: 1 GB available space Sound Card: DirectX compatible, with latest drivers
What platforms is STEM Defense available on?
STEM Defense is available on Windows PC, macOS.
Is STEM Defense worth buying?
STEM Defense has 100% positive reviews from 1 players.
When was STEM Defense released?
STEM Defense was released on Jun 7, 2024.
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